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DeCS
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Descriptor English:
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Receptors, Polymeric Immunoglobulin
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Descriptor Spanish:
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Receptores de Inmunoglobulina Polimérica
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Descriptor Portuguese:
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Receptores de Imunoglobulina Polimérica
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Synonyms English:
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Ig Receptor, Polymeric
Immunoglobulin Receptor, Polymeric
Immunoglobulin Receptors, Polymeric
Poly Ig Receptor
Poly-Ig Receptor
Polyimmunoglobulin Receptor
Polymeric Ig Receptor
Polymeric Immunoglobulin Receptor
Polymeric Immunoglobulin Receptors
Receptor, Poly-Ig
Receptor, Polyimmunoglobulin
Receptor, Polymeric Ig
Receptor, Polymeric Immunoglobulin
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Tree Number:
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D12.776.543.750.705.871.700
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Definition English:
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Specialized Fc receptors (RECEPTORS, FC) for polymeric immunoglobulins, which mediate transcytosis of polymeric IMMUNOGLOBULIN A and IMMUNOGLOBULIN M into external secretions. They are found on the surfaces of epithelial cells and hepatocytes. After binding to IMMUNOGLOBULIN A, the receptor-ligand complex undergoes endocytosis, transport by vesicle, and secretion into the lumen by exocytosis. Before release, the part of the receptor (SECRETORY COMPONENT) that is bound to IMMUNOGLOBULIN A is proteolytically cleaved from its transmembrane tail. (From Rosen et al., The Dictionary of Immunology, 1989) |
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History Note English:
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96
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Allowable Qualifiers English:
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Record Number:
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32632
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Unique Identifier:
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D019056
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Occurrence in VHL:
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Similar:
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DeCS
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